Cambridgeshire-led study recruiting 7,500 people on psychosis care

Summarised from 2 outlets · Updated 19 Oct, 05:01 · Archive

A UK-wide study led by Cambridgeshire and Peterborough NHS Foundation Trust aims to improve early intervention in psychosis.

A major research programme to improve early intervention in psychosis is being led by Cambridgeshire and Peterborough NHS Foundation Trust. The Early Intervention Mission is a UK-wide study focused on early identification, monitoring and personalised care for individuals experiencing a first episode of psychosis. Symptoms can include hallucinations, hearing voices, delusions and disorganised thinking.

The study aims to recruit up to 7,500 people in the early stages of psychosis, along with up to 500 healthy control participants. Participants identified through health service records will be invited to take part remotely via NHS England's DigiTrials service. Where suitable, individuals may attend an initial research visit to provide a blood or saliva sample and complete questionnaires and cognitive tasks. Those with psychosis will be followed every six months for up to three years using digital questionnaires.

Professor Graham Murray, consultant psychiatrist at CPFT and professor of psychiatry and neuroscience at the University of Cambridge, said the research will help identify who is at risk of early psychosis and how best to target preventative treatment. Data will be stored securely in the Mental Health Mission Trusted Research Environment and used to investigate immune markers, genetics and social influences on psychosis development and progression. The study is informed by individuals with lived experience and intends to create a long-term resource to support future clinical trials and personalised treatment approaches.

How it is being reported

• Cambridgeshire-led study to recruit 7,500 people to improve psychosis careA major research programme to improve early intervention in psychosis is being led by Cambridgeshire and Peterborough.Ely Standard · 19 Oct, 04:00
• Cambridgeshire-led study to recruit 7,500 people to improve psychosis careA major research programme to improve early intervention in psychosis is being led by Cambridgeshire and Peterborough.Cambs Times · 19 Oct, 04:00

In this story: Cambridgeshire and Peterborough NHS Foundation Trust · University of Cambridge · Graham Murray · NHS England · Cambridgeshire · Peterborough

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